彰基自2005年起開始於巴布亞紐幾內亞進行短期醫療服務，至今已派遣77個醫療團前往服務國家遍及亞洲、南太平洋、非洲及加勒比海地區，總服務國家超過十四國，直接服務人次超過三萬人以上，專業的醫療表現及用心，深獲當地政府與民眾肯定與讚許。
Since 2005， Changhua Christian Hospital began their short-term medical mission in Papua New Guinea. Till 2017， CCH has organized more than 77 medial teams to Swaziland， Papua New Guinea， St. Lucia， St. Vincent， Thailand， Vietnam， Myanmar and Mongolia for short-term voluntary service. More than 30，000 patients received the service directly and gave highly feedback and treasure friendship to CCH.
為提升友好國家醫療水準，彰基也接受友好國家派遣醫事、研究人員及學生至本院交流。透過臨床實務及經驗分享，讓學員於結訓返國後能持續發揮教學種子的力量，有效提升當地醫療人力資源素質。
In order to strengthen the technologies and share the new knowledge of health promotion， CCH hosted staffs， scholars and students from cooperative countries by attending advance training. The trainees could act as the seed to spread the innovative ideas and updated technology to build the capacity of their organization when they back to their own country.
彰基也致力於與當地社區組織如社福機構、學校、社區團體等進行跨國合作，針對在地需求進行評估規劃，提供公共衛生綜合性專業協助。例如越南順化兒童營養改善計畫、尼泊爾婦女衛教計畫、聖露西亞糖尿病地理圖譜計畫等，都在當地獲得熱烈迴響。
CCH aimed at strengthening the cooperation with local community organizations such as social welfare networks， schools and community associations. By assessing the local needs and provide comprehensive professional support， CCH carried out the public health projects under severely limited resource. “Children malnutrition improvement project” in Vietnam， “Health promotion and education project “in rural Nepal and the “Diabetes geographic mapping program “in St. Lucia are all successfully conducted.
在技術交流與跨國醫療合作外，彰基也將汰換更新但功能正常之儀器設備或硬體設施整理後捐贈給開發中國家使用。除協助提昇醫療效能外，也改善整體醫療照護環境。
The Hospital also donated used but still good equipments to developing countries such as Congo， Kenya， Nepal and St. Vincent to strengthen the hospital capacities.
