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| 陳守棟 主治醫師
一、學歷: 台北醫學院醫科畢業
二、經歷: 1.彰化基督教醫院乳房外科主治醫師 2.彰基體系合作醫院員生醫院院長 3.台灣乳房醫學會常務理事 4.中華民國癌症醫學會理事、監事 5.彰化縣癌症衛教關懷學會理事長 6.國家衛生研究院乳癌研究委員會委員 7.國科會研究計畫主持人 8.教育部部訂助理教授 9.彰化基督教醫院外科部主任 10.彰化基督教醫院全方位乳房腫瘤中心創辦首任主任 11.台灣內視鏡外科醫學會理事 12.台灣外科醫學會理事 13.台灣腫瘤外科專科醫師訓練指導醫師 14.中華民國醫用超音波學會理事 15.台灣消化系外科醫學會理事 16.彰化地檢處義務法醫 17.彰化縣醫師公會常務理事 18.財團法人賴和文教基金會董事長 19.彰化縣綠色資源人文保育協會理事長
三、國外進修: 1.美國紐約Memorial Sloan-Kettering Cancer Center癌症中心短期進修 2.日本國立癌症中心短期進修 3.法國巴黎Breast Oncoplastic Masterclass乳房腫瘤整形專家訓練課程 4.美國University of Pittsburgh匹茲堡大學醫學中心短期進修 5.美國紐約大學醫學院附設醫院New York University (NYU)短期進修
四、醫師證照: 1.台灣外科醫學會 外科專科醫師 2.台灣乳房醫學會 乳房專科醫師 3.台灣臨床腫瘤醫學會 臨床腫瘤專科醫師 4.中華民國癌症醫學會 腫瘤外科專科醫師 5.中華民國醫用超音波學會 超音波專業醫師 6.台灣內視鏡外科醫學會 內視鏡外科專科醫師 7.台灣消化系外科醫學會 消化系外科專科醫師 8.中華民國癌症醫學會 腫瘤外科專科醫師訓練指導醫師
五、論文著述: 1.Lai HW, Tseng LM, Chang TW, Kuo YL, Hsieh CM, Chen ST, Kuo SJ, Su CC, Chen DR. The prognostic significance of metaplastic carcinoma of the breast (MCB) – A case controlled comparison study with infiltrating ductal carcinoma. Breast 2013 Jun 17. (SCI)
2.Tseng HS, Lin C, Chan SE, Chien SY, Kuo SJ, Chen ST, Chang TW, Chen DR. Pure mucinous carcinoma of the breast: clinicopathologic characteristics and long-term outcome among Taiwanese women. World J Surg Oncol 2013 Jun 14;11:139. (SCI)
3.Chen ST, Chen DR, Fang JP, Lin PH. 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breast cancer cells through alteration of CYP1A1 and CYP1B1 expression. Breast Cancer 2013 May 23. (SCI)
4.French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, Gonzalez-Neira A, Alonso MR, Herrero D, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Conroy D, Dennis J, Bolla MK, Wang Q, Hopper JL, Southey MC, Schmidt MK, Broeks A, Verhoef S, Cornelissen S, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Loehberg CR, Ekici AB, Beckmann MW, Peto J, dos Santos Silva I, Johnson N, Aitken Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guenel P, Truong T, Laurent-Puig P, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Zamora MP, Arias Perez JI, Benitez J, Anton-Culver H, Brenner H, Muller H, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Engel C, Brauch H, Hamann U, Justenhoven C; GENICA Network, Aaltonen K, Heikkila P, Aittomaki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Sueta A, Bogdanova NV, Antonenkova NN, Dork T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D, Peeters S, Smeets A, Floris G, Chang-Claude J, Rudolph A, Nickels S, Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Sardella D, Couch FJ, Wang X, Pankratz VS, Lee A, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labreche F, Dumont M, Teo SH, Yip CH, Ng CH, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devilee P, Seynaeve C, Garcia-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring D, Schoof N, Hooning MJ, Martens JW, Collee JM, Tilanus-Linthorst M, Hall P, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A, Balasubramanian SP, Blot W, Signorello LB, Cai Q, Pharoah PD, Healey CS, Shah M, Pooley KA, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Sng JH, Sim X, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, McKay J, Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK, Shen CY, Hsiung CN, Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N, Schoemaker MJ, Ponder BA, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM. Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013 Apr 4;92(4):489-503. (SCI)
5.Lai HW, Wu HK, Kuo SJ, Chen ST, Tseng HS, Tseng LM, Chen DR. Differences in accuracy and underestimation rates for 14- versus 16-gauge core needle biopsies in ultrasound-detectable breast lesions. Asian J Surg 2013 Apr;36(2):83-8. (SCI)
6.Hein R, Flesch-Janys D, Dahmen N, Beckmann L, Lindstrom S, Schoof N, Czene K, Mittelstras K, Illig T, Seibold P, Behrens S, Humphreys K, Li J, Liu J, Olson JE, Wang X, Hankinson SE, Truong T, Menegaux F, Dos Santos Silva I, Johnson N; GENICA Network, Chen ST, Yu JC, Ziogas A, Kataja V, Kosma VM, Mannermaa A, Anton-Culver H, Shen CY, Brauch H, Peto J, Guenel P, Kraft P, Couch FJ, Easton DF, Hall P, Chang-Claude J. A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication. Breast Cancer Res Treat 2013 Apr;138(2):529-42.
7.Liao SF, Li SH, Huang HY, Chen ST, Kuo SJ, Chen DR, Wei TS. The efficacy of complex decongestive physiotherapy (CDP) and predictive factors of lymphedema severity and response to CDP in breast cancer-related lymphedema (BCRL). Breast 2013 Jan 12. (SCI)
8.Chen ST, Lin CC, Liu YS, Lin C, Hung PT, Jao CW, Lin PH. Airborne particulate collected from central Taiwan induces DNA strand breaks, Poly(ADP-ribose) polymerase-1 activation, and estrogen-disrupting activity in human breast carcinoma cell lines. J Environ Sci Health A Tox Hazard Subst Environ Eng 2013;48(2):173-81. (SCI)
9.Lo LC, Chen CY, Chen ST, Chen HC, Lee TC, Chang CS. Therapeutic efficacy of traditional Chinese medicine, Shen-Mai San, in cancer patients undergoing chemotherapy or radiotherapy: study protocol for a randomized, double-blind, placebo-controlled trial. Trials 2012 Dec 3;13(1):232. (SCI)
10.Lin CC, Lin PY, Ko CJ, Chen YL, Chen ST, Kuo SJ. Hepatic resection for bilateral hepatolithiasis: a 20-year experience. ANZ J Surg 2012 Sep 26. (SCI)
11.Yang LH, Tseng HS, Lin C, Chen LS, Chen ST, Kuo SJ, Chen DR. Survival benefit of tamoxifen in estrogen receptor-negative and progesterone receptor-positive low grade breast cancer patients. J Breast Cancer 2012 Sep;15(3):288-95. (SCI)
12.Tseng HS, Wu HK, Chen ST, Kuo SJ, Huang YL, Chen DR. Speckle reduction imaging of breast ultrasound does not improve the diagnostic performance of morphology-based CAD System. J Clin Ultrasound 2012 Jan;40(1):1-6. (SCI)
13.Lin C, Chien SY, Kuo SJ, Chen LS, Chen ST, Lai HW, Chang TW, Chen DR. A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan. Jpn J Clin Oncol 2012 Jan 27. (SCI)
14.Yu JC, Hsiung CN, Hsu HM, Bao BY, Chen ST, Hsu GC, Chou WC, Hu LY, Ding SL, Cheng CW, Wu PE, Shen CY. Genetic variation in the genome-wide predicted estrogen response element-related sequences is associated with breast cancer development. Breast Cancer Research 2011 Jan 31;13(1):R13. (SCI)
15.Yang XR, Chang-Claude J, Goode EL, Couch FJ, Nevanlinna H, Milne RL, Gaudet M, Schmidt MK, Broeks A, Cox A, Fasching PA, Hein R, Spurdle AB, Blows F, Driver K, Flesch-Janys D, Heinz J, Sinn P, Vrieling A, Heikkinen T, Aittomaki K, Heikkila P, Blomqvist C, Lissowska J, Peplonska B, Chanock S, Figueroa J, Brinton L, Hall P, Czene K, Humphreys K, Darabi H, Liu J, Van 't Veer LJ, van Leeuwen FE, Andrulis IL, Glendon G, Knight JA, Mulligan AM, O'Malley FP, Weerasooriya N, John EM, Beckmann MW, Hartmann A, Weihbrecht SB, Wachter DL, Jud SM, Loehberg CR, Baglietto L, English DR, Giles GG, McLean CA, Severi G, Lambrechts D, Vandorpe T, Weltens C, Paridaens R, Smeets A, Neven P, Wildiers H, Wang X, Olson JE, Cafourek V, Fredericksen Z, Kosel M, Vachon C, Cramp HE, Connley D, Cross SS, Balasubramanian SP, Reed MW, Dork T, Bremer M, Meyer A, Karstens JH, Ay A, Park-Simon TW, Hillemanns P, Arias Perez JI, Menendez Rodriguez P, Zamora P, Benitez J, Ko YD, Fischer HP, Hamann U, Pesch B, Bruning T, Justenhoven C, Brauch H, Eccles DM, Tapper WJ, Gerty SM, Sawyer EJ, Tomlinson IP, Jones A, Kerin M, Miller N, McInerney N, Anton-Culver H, Ziogas A, Shen CY, Hsiung CN, Wu PE, Yang SL, Yu JC, Chen ST, Hsu GC, Haiman CA, Henderson BE, Le Marchand L, Kolonel LN, Lindblom A, Margolin S, Jakubowska A, Lubinski J, Huzarski T, Byrski T, Gorski B, Gronwald J, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Kriege M, Tilanus-Linthorst MM, Collee M, Wang-Gohrke S, Pylkas K, Jukkola-Vuorinen A, Mononen K, Grip M, Hirvikoski P, Winqvist R, Mannermaa A, Kosma VM, Kauppinen J, Kataja V, Auvinen P, Soini Y, Sironen R, Bojesen SE, Orsted DD, Kaur-Knudsen D, Flyger H, Nordestgaard BG, Holland H, Chenevix-Trench G, Manoukian S, Barile M, Radice P, Hankinson SE, Hunter DJ, Tamimi R, Sangrajrang S, Brennan P, McKay J, Odefrey F, Gaborieau V, Devilee P, Huijts PE, Tollenaar RA, Seynaeve C, Dite GS, Apicella C, Hopper JL, Hammet F, Tsimiklis H, Smith LD, Southey MC, Humphreys MK, Easton D, Pharoah P, Sherman ME, Garcia-Closas M. Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. Journal of the National Cancer Institute 2011 Feb 2;103(3):250-63. (SCI)
16.Lu YS, Chen DR, Tseng LM, Yeh DC, Chen ST, Hsieh CM, Wang HC, Yeh HT, Kuo SH, Huang CS. Phase II study of docetaxel, capecitabine, and cisplatin as neoadjuvant chemotherapy for locally advanced breast cancer. Cancer Chemotherapy and Pharmacology 2011 Jun;67(6):1257-63. (SCI)
17.Lai HW, Kuo SJ, Chen LS, Chi CW, Chen ST, Chang TW, Chen DR. Prognostic significance of triple negative breast cancer at tumor size 1 cm and smaller. European Journal of Surgical Oncology 2011 Jan;37(1):18-24. (SCI)
18.Chen ST, Lai HW, Tseng HS, Chen LS, Kuo SJ, Chen DR. Correlation of Histologic Grade With Other Clinicopathological Parameters, Intrinsic Subtype, and Patients' Clinical Outcome in Taiwanese Women. Japanese Journal of Clinical Oncology 2011 Nov 8;41(12):1327-35. (SCI)
19.Chen ST, Kuo SJ, Wu HK, Chen LS, Chen DR. Power Doppler breast ultrasound: association of vascularization and ER/c-erbB-2 co-expression in invasive breast carcinoma. Breast Cancer 2011 Nov 29. (SCI)
20.Chen DR, Chen ST, Wang TW, Tsai CH, Wei HH, Chen GJ, Yang TC, Lin C, Lin PH. Characterization of estrogen quinone-derived protein adducts and their identification in human serum albumin derived from breast cancer patients and healthy controls. Toxicolgy Letters 2011 May 10;202(3):244-52. (SCI)
21.Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C, Tchatchou S, Bojesen SE, Nordestgaard BG, Flyger H, Orsted DD, Kaur-Knudsen D, Milne RL, Perez JI, Zamora P, Rodriguez PM, Benitez J, Brauch H, Justenhoven C, Ko YD, Hamann U, Fischer HP, Bruning T, Pesch B, Chang-Claude J, Wang-Gohrke S, Bremer M, Karstens JH, Hillemanns P, Dork T, Nevanlinna HA, Heikkinen T, Heikkila P, Blomqvist C, Aittomaki K, Aaltonen K, Lindblom A, Margolin S, Mannermaa A, Kosma VM, Kauppinen JM, Kataja V, Auvinen P, Eskelinen M, Soini Y, Chenevix-Trench G, Spurdle AB, Beesley J, Chen X, Holland H, Lambrechts D, Claes B, Vandorpe T, Neven P, Wildiers H, Flesch-Janys D, Hein R, Loning T, Kosel M, Fredericksen ZS, Wang X, Giles GG, Baglietto L, Severi G, McLean C, Haiman CA, Henderson BE, Le Marchand L, Kolonel LN, Alnaes GG, Kristensen V, Borresen-Dale AL, Hunter DJ, Hankinson SE, Andrulis IL, Mulligan AM, O'Malley FP, Devilee P, Huijts PE, Tollenaar RA, Van Asperen CJ, Seynaeve CS, Chanock SJ, Lissowska J, Brinton L, Peplonska B, Figueroa J, Yang XR, Hooning MJ, Hollestelle A, Oldenburg RA, Jager A, Kriege M, Ozturk B, van Leenders GJ, Hall P, Czene K, Humphreys K, Liu J, Cox A, Connley D, Cramp HE, Cross SS, Balasubramanian SP, Reed MW, Dunning AM, Easton DF, Humphreys MK, Caldas C, Blows F, Driver K, Provenzano E, Lubinski J, Jakubowska A, Huzarski T, Byrski T, Cybulski C, Gorski B, Gronwald J, Brennan P, Sangrajrang S, Gaborieau V, Shen CY, Hsiung CN, Yu JC, Chen ST, Hsu GC, Hou MF, Huang CS, Anton-Culver H, Ziogas A, Pharoah PD, Garcia-Closas M. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Human Molecular Genetics 2011 Aug 15;20(16):3289-303. (SCI)
22.#Lin C, #Chen ST, Chien SY, Kuo SJ, Chen DR. Use of high-dose nandrolone aggravates septic shock in a mouse model. The Kaohsiung Journal of Medical Sciences 2011 Jun;27(6):222-9. (SCI)
23.#Chang HC, #Chen ST, Chien SY, Kuo SJ, Tsai HT, Chen DR. Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction. Human & Experimental Toxicology 2011 Oct;30(10):1657-65. (SCI)
24.Ming-Shiean H, Yu JC, Wang HW, Chen ST, Hsiung CN, Ding SL, Wu PE, Shen CY, Cheng CW. Synergistic effects of polymorphisms in DNA repair genes and endogenous estrogen exposure on female breast cancer risk. Annals of Surgical Oncology 2010 Mar;17(3):760-71. (SCI)
25.Kuo SJ, Chen M, Ma GC, Chen ST, Chang SP, Lin WY, Chen YC, Lee TH, Lin TT, Liu CS. Number of somatic mutations in the mitochondrial D-loop region indicates poor prognosis in breast cancer, independent of TP53 mutation. Cancer Genetics and Cytogenetics 2010 Sep;201(2):94-101. (SCI)
26.Hsieh CS, Chen YL, Lee MH, Chang HC, Chen ST, Kuo SJ. A lower costly laparoscopic appendectomy: our experience of more than 2000 cases. International Journal of Surgery 2010;8(2):140-3. (SCI)
27.Ding SL, Yu JC, Chen ST, Hsu GC, Hsu HM, Ho JY, Lin YH, Chang CC, Fann CS, Cheng CW, Wu PE, Shen CY. Diverse associations between ESR1 polymorphism and breast cancer development and progression. Clinical Cancer Research 2010 Jul 1;16(13):3473-84. (SCI)
28.Liao SF, Lee YF, Chen ST, Kuo SJ, Liang WC, Wei TS, Liu MT. Incidence and Risk Factors Analysis of Lymphedema Secondary to Breast Cancer. Taiwan J Phy Med Rehabil (臺灣復健醫學雜誌) 2009;37(4):217-25.
29.Yu JC, Ding SL, Chang CH, Kuo SH, Chen ST, Hsu GC, Hsu HM, Hou MF, Jung LY, Cheng CW, Wu PE, Shen CY. Genetic susceptibility to the development and progression of breast cancer associated with polymorphism of cell cycle and ubiquitin ligase genes. Carcinogenesis 2009 Sep;30(9):1562-70. (SCI)
30.Tseng HS, Chen YL, Chen ST, Wu YC, Kuo SJ, Chen LS, Wu HK, Chen DR. The management of papillary lesion of the breast by core needle biopsy. European Journal of Surgical Oncology 2009 Jul 17;35(1):21-4. (SCI)
31.Lin CH, Huang CL, Chuang MC, Wang YJ, Chen DR, Chen ST, *Lin PH. Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells. Toxicology Letters 2009 Jul 10;188(1):11-9. (SCI)
32.Hsiao YH, Huang YL, Kuo SJ, Liang WM, Chen ST, Chen DR. Characterization of benign and malignant solid breast masses in harmonic 3D power Doppler imaging. European Journal of Radiology 2009 Jul;71(1):89-95. (SCI)
33.Ding SL, Yu JC, Chen ST, Hsu GC, Kuo SJ, Lin YH, Wu PE, Shen CY. Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility. Carcinogenesis 2009 Jan;30(1):43-9. (SCI)
34.Chen ST, Hsiao YH, Huang YL, Kuo SJ, Tseng HS, Wu HK, Chen DR. Comparative analysis of logistic regression, support vector machine and artificial neural network for the differential diagnosis of benign and malignant solid breast tumors by the use of three-dimensional power Doppler imaging. Korean Journal of Radiology 2009 Sep-Oct;10(5):464-71. (SCI)
35.Ahmed S, Thomas G, Ghoussaini M, Healey CS, Humphreys MK, Platte R, Morrison J, Maranian M, Pooley KA, Luben R, Eccles D, Evans DG, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Stratton MR, Rahman N, Jacobs K, Prentice R, Anderson GL, Rajkovic A, Curb JD, Ziegler RG, Berg CD, Buys SS, McCarty CA, Feigelson HS, Calle EE, Thun MJ, Diver WR, Bojesen S, Nordestgaard BG, Flyger H, Dork T, Schurmann P, Hillemanns P, Karstens JH, Bogdanova NV, Antonenkova NN, Zalutsky IV, Bermisheva M, Fedorova S, Khusnutdinova E, Kang D, Yoo KY, Noh DY, Ahn SH, Devilee P, van Asperen CJ, Tollenaar RA, Seynaeve C, Garcia-Closas M, Lissowska J, Brinton L, Peplonska B, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, Hopper JL, Southey MC, Smith L, Spurdle AB, Schmidt MK, Broeks A, van Hien RR, Cornelissen S, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Schmutzler RK, Burwinkel B, Bartram CR, Meindl A, Brauch H, Justenhoven C, Hamann U, Chang-Claude J, Hein R, Wang-Gohrke S, Lindblom A, Margolin S, Mannermaa A, Kosma VM, Kataja V, Olson JE, Wang X, Fredericksen Z, Giles GG, Severi G, Baglietto L, English DR, Hankinson SE, Cox DG, Kraft P, Vatten LJ, Hveem K, Kumle M, Sigurdson A, Doody M, Bhatti P, Alexander BH, Hooning MJ, van den Ouweland AM, Oldenburg RA, Schutte M, Hall P, Czene K, Liu J, Li Y, Cox A, Elliott G, Brock I, Reed MW, Shen CY, Yu JC, Hsu GC, Chen ST, Anton-Culver H, Ziogas A, Andrulis IL, Knight JA, Beesley J, Goode EL, Couch F, Chenevix-Trench G, Hoover RN, Ponder BA, Hunter DJ, Pharoah PD, Dunning AM, Chanock SJ, Easton DF. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nature Genetics 2009 May;41(5):585-90. (SCI)
36.Chen YL, Talbot AR, Chang HC, Chen ST, Kuo SJ, Fang HY. Limited hepatic resection by laparoscopy-assisted mini-laparotomy for the treatment of hepatocellular carcinoma in cirrhotic patients. International Surgery 2008 May-Jun;93(3):127-32. (SCI)
37.Lo YL, Yu JC, Chen ST, Hsu GC, Mau YC, Yang SL, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the mitotic checkpoint genes: a multigenic study on cancer susceptibility. Carcinogenesis 2007 May;28(5):1079-86. (SCI)
38.Ding SL, Yu JC, Chen ST, Hsu GC, Shen CY. Genetic variation in the premature aging gene WRN: a case-control study on breast cancer susceptibility. Cancer Epidemiology, Biomarkers & Prevention 2007 Feb;16(2):263-9. (SCI)
39.Yu JC, Hsu HM, Chen ST, Hsu GC, Huang CS, Hou MF, Fu YP, Cheng TC, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility. Journal of Biomedical Science 2006 May;13(3):419-32. (SCI)
40.Wu GH, Chen LS, Chang KJ, Hou MF, Chen SC, Liu TJ, Huang CS, Hsu GC, Yu CC, Jeng LL, Chen ST, Chou YH, Wu CY, Shin-Lan K, Chen TH. Evolution of breast cancer screening in countries with intermediate and increasing incidence of breast cancer. Journal of Medical Screening 2006;13 Suppl 1:S23-7. (SCI)
41.Lo YL, Yu JC, Chen ST, Yang HC, Fann CS, Mau YC, Shen CY. Breast cancer risk associated with genotypic polymorphism of the mitosis-regulating gene Aurora-A/STK15/BTAK. International Journal of Cancer 2005 Jun 10;115(2):276-83. (SCI)
42.Lee TY, Chen YL, Chang HC, Yang LH, Chan CP, Chen ST, Kuo SJ. Anatomic resection for severe blunt liver trauma. International Surgery 2005 Nov-Dec;90(5):266-9. (SCI)
43.Cheng TC, Chen ST, Huang CS, Fu YP, Yu JC, Cheng CW, Wu PE, Shen CY. Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: a multigenic study on cancer susceptibility. International Journal of Cancer 2005 Jan 20;113(3):345-53. (SCI)
44.Chen WM, Chang RF, Kuo SJ, Chang CS, Moon WK, Chen ST, Chen DR. 3-D ultrasound texture classification using run difference matrix. Ultrasound in Medicine & Biology 2005 Jun;31(6):763-70. (SCI)
45.Chen ST, Choo KB, Hou MF, Yeh KT, Kuo SJ, Chang JG. Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers. Carcinogenesis 2005 Jul;26(7):1241-6. (SCI)
46.Chen DR, Chang RF, Chen CJ, Ho MF, Kuo SJ, Chen ST, Hung SJ, Moon WK. Classification of breast ultrasound images using fractal feature. Clinical Imaging 2005 Jul-Aug;29(4):235-45. (SCI)
47.Lin SY, Yeh KT, Chen WT, Chen HC, Chen ST, Chiou HY, Chang JG. Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features. Oncology Reports 2004 Feb;11(2):341-8. (SCI)
48.Lin SY, Yeh KT, Chen WT, Chen HC, Chen ST, Chang JG. Promoter CpG methylation of caveolin-1 in sporadic colorectal cancer. Anticancer Research 2004 May-Jun;24(3a):1645-50. (SCI)
49.Liao SF, Huang MS, Li SH, Chen IR, Wei TS, Kuo SJ, Chen ST, Hsu JC. Complex decongestive physiotherapy for patients with chronic cancer-associated lymphedema. Journal of the Formosan Medical Association 2004 May;103(5):344-8. (SCI)
50.Chen ST, Lin SY, Yeh KT, Kuo SJ, Chan WL, Chu YP, Chang JG. Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers. International Journal of Molecular Medicine 2004 Oct;14(4):577-82. (SCI)
51.Bau DT, Fu YP, Chen ST, Cheng TC, Yu JC, Wu PE, Shen CY. Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1. Cancer Research 2004 Jul 15;64(14):5013-9. (SCI)
52.Lam CW, Kuo SJ, Chang HC, Chen ST, Chen YL, Yang LH, Hsieh CS. Pseudomyxoma peritonei, origin from appendix: report of cases with images. International Surgery 2003 Jul-Sep;88(3):133-6. (SCI)
53.Fu YP, Yu JC, Cheng TC, Lou MA, Hsu GC, Wu CY, Chen ST, Wu HS, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility. Cancer Research 2003 May 15;63(10):2440-6. (SCI)
54.Chen YL, Kuo SJ, Yang LH, Chen ST, Tsai JH, Chang HC. Extrahepatic division of the right hepatic vein in right hepatectomy for blunt liver trauma. International Surgery 2003 Jan-Mar;88(1):15-20. (SCI)
55.Chen ST, Chen RA, Kuo SJ, Chien YC. Mutational screening of breast cancer susceptibility gene 1 from early onset, bi-lateral, and familial breast cancer patients in Taiwan. Breast Cancer Research and Treatment 2003 Jan;77(2):133-43. (SCI)
56.Chen ST, Chen JC, Hou MF, Yeh KT, Lee TP, Chen CM, Shih MC, Chang JG. Sulfotransferase lAl is a Risk Factor for Breast Cancer in Young Women Mid-Taiwan J Med (中臺灣醫學科學雜誌) 2003;8(2):59-65.
57.Chan CP, Yang LH, Chang HC, Chen YL, Chen ST, Kuo SJ, Tsai PC. An easier technique for minimally invasive video-assisted thyroidectomy. International Surgery 2003 Apr-Jun;88(2):109-13. (SCI)
58.Chan CP, Chen YL, Chang HC, Chen ST, Kuo SJ, Tsai PC, Chang HM. Repeated Hepatectomies for Follicular Dendritic Cell Tumor of Liver: A Case Report. Changhua Journal of Medicine (彰化醫學) 2003;8(1):55-9.
59.Chan CP, Chang HC, Chen YL, Yang LH, Chen ST, Kuo SJ, Tsai PC. A 10-year experience of unsuspected gallbladder cancer after laparoscopic cholecystectomy. International Surgery 2003 Jul-Sep;88(3):175-9. (SCI)
60.Hsieh CS, Chen YL, Yang LH, Chan SE, Chang HC, Chen ST, Kuo SJ. Transparenchymal retraction maneuver: a simple technique in laparoscopic hepatectomy. International Surgery 2002 Jan-Mar;87(1):45-7. (SCI)
61.Hou MF, Chen ST, Chen JC, Yeh KT, Lee TP, Chen CM, Shih MC, Lin CC, Chang JG. Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. International Journal of Molecular Medicine 2002 Nov;10(5):609-12. (SCI)
62.Kun-Tu Yeh MD, Jan-Gowth Chang MD, Yi-Jen Chen MD, Shou-Tung Chen MD, Shi-Yau Yu MD, Mu-Ching Shih MD, Liuh-I Perng BS, Jyh-Chwan Wang MS, Matty Tsai MT, Chih-Peng Chang MD. Mutation Analysis of the putative tumor suppressor gene PTEN/MMAC1 in hepatocellular carcinoma.Cancer Investigation 2000;18(2):123-129.
63.Jen-Hsiang Tsai, Yih-Shou Hsieh, Shou-Yen Kuo, Shou-Tung Chen, Shi-Yau Yu, Chih-Yang Huang, Ai-Chi Chang, Yi-Wei Wang, Min-Ting Tsai, Jer-Yuh Liu. Alteration in the expression of protein kinase C isoforms in human hepatocellular carcinoma. Cancer Letters 2000;161:171-175.
64.Yao-Li Chen, Shou-Jen Kuo, Shou-Tung Chen, Hung-Chi Chang, Shi-Yau Yu, Li-Heng Yang, Szu-Erh Chan. Preoperative chemoembolization for the treatment of hepatocellular carcinomas demonstrating complicated anatomical relationships. Formosan J Surg 2000;33:171-177.
65.Hung-Chi Chang, Shou-Tung Chen, Li Heng Yang, Yao-Li Chen, Shi-Yau Yu, Szu-Erh Chan. The role of laparoscopic cholecystectomy in treating gangrenous cholecystitis. Formosan J Surg 1999;32:160-164.
66.Shou-Tung Chen, Shi-Yau Yu, Matty Tsai, Kun-Tu Yeh, Jyh-Chwan Wang, Min-Chih Kao, Mu-Ching Shih, and Jan-Gowth Chang. Mutation analysis of the putative tumor suppression gene PTEN/MMAC1 in sporadic breast cancer. Breast Cancer Research and Treatment 1999;55:85-89.
六、基礎醫學研究: 1.轉譯醫學資源中心之臨床試驗合作聯盟:乳癌II。計劃期間:2012/12/1~2013/11/30。支援機關:行政院國家科學委員會。擔任共同主持人。
2.轉譯醫學資源中心之臨床試驗合作聯盟:乳癌。計劃期間: 2011/12/1~2012/11/30。支援機關:行政院國家科學委員會。擔任共同主持人。
3.多氯聯苯所調控之基因表現改變對人類乳癌細胞誘發核酸損壞及修補作用 之影響。計劃期間:2009/8/1~2011/7/31。支援機關:行政院國家科學委員會。擔任主持人。
4.死亡相關基因在乳癌表現及相關機轉的探討。計劃期間:2007/8/1~2009/7/31。支援機關:行政院國家科學委員會。擔任主持人。
5.生物週期基因在乳癌的表現。計劃期間:2006/8/1~2007/7/31。支援機關:行政院國家科學委員會。擔任主持人。
6.早期介入徒手淋巴引流及運動對乳癌腋下淋巴清除手術後之併發症及腋網症候群的影響。計劃期間:2006/8/1~2007/7/31。支援機關:行政院國家科學委員會。擔任共同主持人。
7.PER1, PER2及PER3在乳癌表現的探討。計劃期間:2005/8/1~2006/7/31。支援機關:行政院國家科學委員會。擔任主持人。
8.PTEN基因多型性與乳癌生成相關研究。計劃期間:2008/1/1~2008/12/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
9.乳房超音波彈性影像研究。計劃期間:2008/1/1~2008/12/31。支援機關:財團法人彰化基督教醫院。擔任總主持人。
10.分裂大災難相關基因在肝癌表現及相關機轉的探討。計劃期間:2007/1/1~2007/12/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
11.β-catenin 促進轉錄因子進入細胞核內關係到乳癌的發展。計劃期間:2006/1/1~2006/12/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
12.利用基因晶片分析肝癌細胞中DNA複製相關基因的表現情形。計劃期間:2006/1/1~2006/12/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
13.使用MPCR分析生理時鐘基因啟動區甲基化乳癌的表現。計劃期間:2006/1/1~2006/12/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
14.Disturbance of circadian gene expressions in breast cancer. 計劃期間:2005/1/1~2005/12/31。支援機關:財團法人彰化基督教醫院。擔任計畫主持人。
15.Correlation between protein expression and epigenetic and mutation changes of Wnt pathway-related genes. 計劃期間:2003/5/1~2004/4/30。支援機關:財團法人彰化基督教醫院。擔任主持人。 16.院。擔任主持人。
17.以血漿DNA微衛星DNA之變異為早期偵測血液乳癌細胞轉移的標幟之研究。計劃期間:2002/9/1~2003/8/30。支援機關:國立彰化師範大學。擔任主持人。
18.Mutational Screening of Cancer Susceptibility Gene 1 from Early-Onset, Bi-lateral, and Familial Breat. 計劃期間:2000/8/1~2001/7/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
19.Sulfotransferase 1A1 is a risk factor for young age breast cancer, but not for other cancers. 計劃期間:2000/8/1~2001/7/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
20.The Relationship between Nonrandom X-Chromosome Inactivation and Breast. 計劃期間:2000/8/1~2001/7/31。支援機關:財團法人彰化基督教醫院。擔任主持人。
21.X染色體非隨機的不活化現象語乳癌發生的關係。計劃期間:2000/8/1~2001/7/31支援機關:國立彰化師範大學。擔任主持人。
七、臨床研究: 1. A Randomised three-arm multi-center comparison of 1 year and 2 years of Herceptin versus no Herceptin in women with Her2-positive primary breast cancer who have completed adjuvant Chemotherapy
2. Does adjuvant Zoledronic acid reduce recurrence in patients with high risk localised breast cancer
3. Docetaxel by 1-hour Infusion Followed by 24-Hour Infusion of Cisplatin plus Capecitabine as Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer
4. An Observational, multicenter study of Zometa in bone metastatic breast caner, prostate cancer or multiple myeloma patients under conditions of normal clinical practice
5. Phase III Randomized, Multi Center Study of Sunitinib Malate (SU011248) or Capecitabine in Subjects with Advanced Breast Cancer who failed both a taxane and an anthracycline chemotherapy regimen or failed with a with a taxane and for whom further anthracycline therapy is not indicated
6. A Phase III Open Label, Randomized Two-Parallel-Arm Multicenter Study of E7389 versus Capecitabine in Patients with Locally Advanced or Metastatic Breast Cancer Previously Treated with Anthracyclines and Taxanes
7. Randomised phase II study of the combination of oral vinorelbine with capecitabine versus gemcitabine in combination with paclitaxel versus gemcitabine in combination with docetaxel as first line chemotherapy in patients with metastatic breast cancer
8. An open-label sunitinib Malate (SU011248) continuation protocol for patients who have completed a prior sunitinib study and are judged by the investigator to have the potential to benefit from sunitinib treatment
9. A Randomized, Multicenter, Phase III Study Comparing the Combination of Pazopanib and Lapatinib versus Lapatinib Monotherapy in Patients with ErbB2 over-expressing Inflammatory Breast Cancer
10. A randomised, multicenter open-label phase III study of neoadjuvant lapatinib, trastuzumab and their combination plus paclitaxel in women with HER2/ErbB2 positive primary breast cancer
11. An international multi-centre open-label 2-arm phase III trial of adjuvant bevacizumab in triple negative breast cancer
12. A Randomized, Open-Label, Phase III Study of Taxane Based Chemotherapy with Lapatinib or Trastuzumab as First-Line Therapy for Patients with Her2/Neu Positive Metastatic Breast Cancer
13. Quality of Life Evaluation of Breast Cancer Patients with Bone Metastasis after Administration of Zometa ( zoledronic acid)
14. An Open-Label, Randomized, Multicenter Study to Evaluate the Use of Zoledronic Acid in the Prevention of Cancer Treatment-Related Bone Loss in Postmenopausal Women with ER+ and/or PgR+ Breast Cancer Receiving Letrozole as Adjuvant Therapy
15. A Randomized, Open-Label, Multicenter, Phase 3 Study of Epoetin Alfa plus Standard Supportive Care versus Standard Supportive Care in Anemic Patients With Metastatic Breast Cancer Receiving First-Line Standard Chemotherapy
16. A phase III, randomized, open-label study to compare pharmacokinetics, efficacy and safety of subcutaneous (SC) trastuzumab with intravenous (IV) trastuzumab administered in women with HER2 positive early breast cancer (EBC)
17. A randomized, 3 arm, multicentre, phase III study to evaluate the efficacy and the safety of T-DM1 combined with pertuzumab or T-DM1 combined with pertuzumab-placebo (blinded for pertuzumab), versus the combination of trastuzumab plus taxane, as first line treatment in HER2- positive progressive or recurrent locally advanced or metastatic breast cancer (MBC)
18. A Double-blind, Randomized Phase II/III Trial of Active Immunotherapy with Globo H-KLH (OPT-822) in Subjects with Metastatic Breast Cancer.
19. A Phase II Randomized Study of Pegylated Liposomal Doxorubicin (Lipo-Dox)- Cyclophosphamide versus Epirubicin- Cyclophosphamide as Adjuvant Chemotherapy in Her2-negative Stage I and II Breast Cancer Patients
20. A Randomized Phase III Study of Docetaxel / Epirubicin versus Tailored Regimens as Neoadjuvant Chemotherapy for Stage II/III Breast Cancer with Tumor Size More Than 3cm.
21. LUX-Breast 1: An open label, randomised phase III trial of BIBW 2992 and vinorelbine versus trastuzumab and vinorelbine in patients with metastatic HER2-overexpressing breast cancer failing one prior trastuzumab treatment
22. A randomized multicenter, double-blind, placebo-controlled comparison of chemotherapy plus trastuzumab plus placebo versus chemotherapy plus trastuzumab plus pertuzumab as adjuvant therapy in patients with operable HER2-positive primary breast cancer |
|
| 陳達人 教授兼主任
一、學歷: 中國醫藥大學醫學士
二、經歷: 乳房外科學教授 中國醫藥大學外科部主治醫師 中國醫藥大學醫學研究所教授 彰化基督教醫院乳房中心主任 彰化基督教醫院醫學研究部主任 彰化基督教醫院外科部部協同主任 彰化基督教醫院乳癌小組召集人 台灣乳房醫學會理事 中華民國醫用超音波學會理事 彰化醫師公會醫師教育召集人 國科會研究計劃主持人(2000~2014) 國科會研究計劃審查委員 中山醫學大學醫學系兼任教授 東海大學資工所兼任教授
三、國外進修: 整型式乳癌切除專家訓練課程 -美國達拉斯 (2009) -法國巴黎外科學院 (2010、2011) -意大利米蘭EIO (2011、2012、2013)
四、國際醫學期刊審查委員 1、European Radiology特聘審查委員 2、Ultrasound in Medicine & Biology 3、Ultrasound obstetrics & Gynecology 4、Eur.J.Surg.Oncol. 5、Breast Cancer Research and Treatment
五、國際醫學期刊編輯委員 Recent Patents on Medical Imaging
六、國際獎項 1999年國際乳房超音波醫學會(日本東京)青年科學家獎
七、專科證照 1、台灣外科醫學會 外科專科醫師 2、台灣乳房醫學會 乳房專科醫師 3、台灣臨床腫瘤醫學會 臨床腫瘤專科醫師 4、中華民國醫用超音波學會 專科醫師暨專科指導醫師 5、中華民國癌症醫學會 腫瘤外科專科醫師暨腫瘤外科專科指導醫師
八、教職 中華民國教育部審定教授
九、國外演講: 2010 日本東北大學 2011 英國諾丁漢國際整型式乳房切除手術醫學會 2013 日本東京大學
十、論文 國際期刊、原著論文(PUBLICATIONS * corresponding author)
1.Dar-Ren Chen*. An optimized technique for all quadrant oncoplasty in women with small- to medium-sized breasts. European Review for Medical and Pharmacological Sciences 2014, in press
2.Lin C, Hsieh WC, Chen DR, Kuo SJ, Yu WF, Hu SW, Sue HJ, Ko MH, Juan CH, Chung KS, Lin PH.: Hemoglobin adducts as biomarkers of estrogen homeostasis: Elevation of estrogenquinones as a risk factor for developing breast cancer in Taiwanese Women Toxicol Lett. 2014 Jan 19
3.Che Lin, Li-Sheng Chen, Shou-Jen Kuo, Dar-Ren Chen*: Adjuvant tamoxifen influences lipid profile in breast cancer patients. Breast Care 2014, in press.
4.Jia-Long Wu, Hsin-Shun Tseng, Li-Heng Yang, Hwa-Koon Wu, Shou-Jen Kuo, Shou-Tung Chen, Dar-Ren Chen*. Prediction of axillary lymph node metastases in breast cancer patients based on pathologic information of the primary tumor. Medical Science Monitor 2014, in press.
5.Chin-Yuan Chang, Shou-Jen Kuo, Hwa-Koon Wu, Yu-Len Huang, Dar-Ren Chen*. Stellate masses and histologic grades in breast cancer. Ultrasound Med Biol. 2014 Jan 22. pii: S0301-5629(13)01149-6. [Epub ahead of print]
6.Hwa-Koon Wu, Hsin-Shun Tseng, Li-Sheng Chen, Shou-Jen Kuo, Ping-Lang Yen, Yu-Len Huang, Dar-Ren Chen*. Flow index of 3D breast ultrasound was strongly correlated with axillary lymph node metastasis in the absence of lymphovascular invasion. Journal of Medical Imaging and Health Informatics 2014, in press.
7.Wu ju, Li CW, Tsai CH, Chou CW, Chen DR, Wang GJ: Synthesis of Antibacterial TiO2/PLGA composite Biofilms Nanomedicine 2014, in press
8.Tseng HS, Lin C, Chan SE, Chien SY, Kuo SJ, Chen ST, Chang TW, Chen DR*. Pure mucinous carcinoma of the breast: clinicopathologic characteristics and long-term outcome among Taiwanese women World J Surg Oncol. 2013 Jun 14;11:139. doi: 10.1186/1477-7819-11-139.
9.Chao TC, Chen DR, Chao TY, Chen SC, Yeh DC, Wang HC, Huang WT, Rau KM, Chang KJ, Yang TL, Lee KD, Tai CJ, Tseng LM, Hou MF Quality of Life Assessment in Taiwanese Patients with Bone Metastases from Breast Cancer Receiving Zoledronic Acid. Anticancer Res. 2013 Dec;33(12):5543-5547
10.Cheng YS, Kuo SJ, Chen DR*.: Sparing sentinel node biopsy through axillary lymph node fine needle aspiration in primary breast cancers World J Surg Oncol. 2013 Nov 20;11(1):296. [Epub ahead of print]
11.Tseng HS, Lin C, Chan SE, Chien SY, Kuo SJ, Chen ST, Chang TW, Chen DR: Availability of convenience stores and adolescent alcohol use in Taiwan: a multilevel analysis of national surveys.World J Surg Oncol. 2013 Jun 14;11(1):139. [Epub ahead of print]
12.Lai HW, Tseng LM, Chang TW, Kuo YL, Hsieh CM, Chen ST, Kuo SJ, Su CC, Chen DR.: The prognostic significance of metaplastic carcinoma of the breast (MCB) - A case controlled comparison study with infiltrating ductal carcinoma. Breast. 2013 Oct;22(5):968-73. doi: 10.1016/j.breast.2013.05.010. Epub 2013 Jun 17.
13.Kuo YL, Chen WC, Yao WJ, Cheng L, Hsu HP, Lai HW, Kuo SJ, Chen DR*, Chang TW*. Validation of Memorial Sloan-Kettering Cancer Center Nomogram for prediction of Non-sentinel lymph node metastasis in Sentinel lymph node positive Breast Cancer Patients An International Comparison. Int J Surg. 2013 May 21. pii: S1743-9191(13)00119-2. doi: 10.1016/j.ijsu.2013.05.005. [Epub ahead of print]
14.Chen ST, Chen DR, Fang JP, Lin PH.: 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breast cancer cells through alteration of CYP1A1 and CYP1B1 expression Breast Cancer. 2013 May 23. [Epub ahead of print]
15.Huang YL, Chen DR*, Chang SC. Three-dimensional region-based segmentation for breast tumors on sonography J Ultrasound Med. 2013 May;32(5):835-46. doi: 10.7863/ultra.32.5.835
16.Lai HW, Wu HK, Kuo SJ, Chen ST, Tseng HS, Tseng LM, Chen DR* : Differences in accuracy and underestimation rates for 14 versus 16-gauge core needle biopsies in ultrasound-detectable lesions (Asian J Surg. 2013 Apr;36(2):83-8. doi: 10.1016/j.asjsur.2012.09.003. Epub 2013 Jan 23
17.Shou-Jen Kuo, Hui-Yi Lin, Su-Yu Chien, Dar-Ren Chen*: SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein (Oncol Rep. 2013 Jul;30(1):125-30. doi: 10.3892/or.2013.2470. Epub 2013 May 15)
18.Chen YL, Yan MY, Chien SY, Kuo SJ, Chen DR, Cheng CY, Su CC: Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro Mol Med Rep. 2013 Mar 20. doi: 10.3892/mmr.2013.1381. [Epub ahead of print]
19.Chien SY, Kuo SJ, Chen DR, Su CC.: Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl 1 and TCTP and increases that of TNF-α and Bax in BxPC 3 pancreatic carcinoma cellsInt J Mol Med. 2013 Jul;32(1):85-92. doi: 10.3892/ijmm.2013.1369. Epub 2013 May 8
20.Lin C, Chen DR, Hsieh WC, Yu WF, Lin CC, Ko MH, Juan CH, Tsuang BJ, Lin PH: Investigation of the cumulative body burden of estrogen-3,4-quinone in breast cancer patients and controls using albumin adducts as biomarkers. Toxicol Lett. 2013 Feb 17;218(3):194-199. doi: 10.1016/j.toxlet.2013.02.004. [Epub ahead of print
21.Liao SF, Li SH, Huang HY, Chen ST, Kuo SJ, Chen DR, Wei TS.: The efficacy of complex decongestive physiotherapy (CDP) and predictive factors of lymphedema severity and response to CDP in breast cancer-related lymphedema (BCRL).Breast. 2013 Jan 12. doi:pii: S0960-9776(12)00262-7. 10.1016/j.breast.2012.12.018. [Epub ahead of print]
22.Huang CY, Chiu TL, Kuo SJ, Chien SY, Chen DR, Su CCTanshinone IIA inhibits the growth of pancreatic cancer BxPC 3 cells by decreasing protein expression of TCTP, MCL 1 and Bcl xLMol Med Report. 2013 Jan 25. doi: 10.3892/mmr.2013.1290. (Epub ahead of print)
23.Tsai HT, Yang SF, Chen DR, Chan SE.: CCL5-28, CCL5-403, and CCR5 genetic polymorphisms and their synergic effect with alcohol and tobacco consumptions increase susceptibility to hepatocellular carcinoma Med Oncol. 2012 Dec;29(4):2771-9. doi: 10.1007/s12032-012-0189-9. Epub 2012 Feb 29.
24.Yang LH, Tseng HS, Lin C, Chen LS, Chen ST, Kuo SJ, Chen DR*: Survival Benefit for Tamoxifen in Estrogen Receptor Negative and Progesterone Receptor Positive Low Grade Breast Cancer J Breast Cancer. 2012 Sep;15(3):288-95. doi: 10.4048/jbc.2012.15.3.288. Epub 2012 Sep 28.
25.Wu CT, Cheng YH, Chen FN, Chen DR, Wei MF, Chang NW: Combined effects of peroxisome proliferator-activated receptor alpha and apolipoprotein e polymorphisms on risk of breast cancer in a taiwanese population J Investig Med. 2012 Dec;60(8):1209-13. doi: 10.231/JIM.0b013e31826be86a
26.Chang NW, Wu CT, Chen DR, Yeh CY, Lin C: High levels of arachidonic acid and peroxisome proliferator-activated receptor-alpha in breast cancer tissues are associated with promoting cancer cell proliferationJ Nutr Biochem. 2012 Aug 16. [Epub ahead of print]
27.Lee YP, Tsai WC, Ko CJ, Rao YK, Yang CR, Chen DR, Yang MH, Yang CC, Tzeng YM: Anticancer effects of eleven triterpenoids derived from Antrodia camphorata Anticancer Res. 2012 Jul;32(7):2727-34.
28.Kuo YL, *Chen DR, Chang TW. Accuracy validation of adjuvant! online in Taiwanese breast cancer patients - a 10-year analysis. BMC Medical Informatics and Decision Making 2012 Sep 17;12(1):108
29.Baselga J, Bradbury I, Eidtmann H, Di Cosimo S, de Azambuja E, Aura C,Chen DR, Hickish T, Patel A, Chan S, Roylance R. : NeoALTTO Study Team Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet. 2012 Feb 18;379(9816):633-40. doi: 10.1016/S0140-6736(11)61847-3. Epub 2012 Jan 17 . 30.Yen PL ,Ho HK,Tseng HS, KUO SJ, Huang YL, PhD, Hong-Ting Chen HT, Chen DR* Vascular morphologic information of three dimensional power Doppler ultrasound is valuable in the classifications of breast lesions. Clin Imaging. 2012 Jul-Aug;36(4):267-71. doi: 10.1016/j.clinimag.2011.11.012. Epub 2012 Jun 8.
31.Shou-Tung Chen, Shou-Jen Kuo, Hwa-Koon Wu, Li-Sheng Chen, Dar-Ren Chen*: Power Doppler breast ultrasound: Association of vascularization and ER/c-erbB-2 co-expression in invasive breast carcinoma Breast Cancer. 2011 Nov 29
32.Tseng HS, Wu HK, Chen ST, Kuo SJ, Huang YL, Chen DR*: Speckle Reduction Imaging of Breast Ultrasound Does Not Improve the Diagnostic Performance in Morphology Based CAD System (J Clin Ultrasound. 2012 Jan;40(1):1-6. )
33.Shou-Tung Chen, Hung-Wen Lai, Hsin-Shun Tseng, Li-Sheng Chen, Shou-Jen Kuo, Dar-Ren Chen*: Correlation of histologic grade with other clinicopathological parameters, intrinsic subtype, and patients’ clinical outcome in Taiwanese women Jpn J Clin Oncol. 2011 Dec;41(12):1327-35..
34.Chang NW, Chen DR, Chen FN, Lin C, Wu CT: HER2 Codon 655 G-Allele Is Associated With Reductions in Plasma High-Density Lipoprotein Levels in Breast Cancer Patients Treated With Tamoxifen J Investig Med. 2011 Dec;59(8):1252-7
35.Chien SY, Kuo SJ, Chen YL, Chen DR, Cheng CY, Su CC: Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo. Mol Med Report. 2011 Oct 14. doi: 10.3892/mmr.2011.631. [Epub ahead of print]
36.Yan MY, Chien SY, Kuo SJ, Chen DR, Su CC. Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expressionInt J Mol Med. 2012 Feb 7. doi: 10.3892/ijmm.2012.908. [Epub ahead of print]
37.Chang HC, Chen ST, Chien SY, Kuo SJ, Tsai HT, Chen DR*: Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunctionHum Exp Toxicol. 2011 Oct;30(10):1657-65. Epub 2011 Feb 7
38.Chen CJ, Lin SE, Lin YM, Lin SH, Chen DR*, Chen CL.: Association of Expression of Kruppel-Like Factor 4 and Kruppel-Like Factor 5 with the Clinical Manifestations of Breast Cancer. Pathol Oncol Res. 2011 Jun 15. [Epub ahead of print]
39.Chan SE, Lai HW, Su CC, Kuo SJ, Chien SY, Lin HY, Chen DR*: Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study Evid Based Complement Alternat Med. 2011;2011:841564. Epub 2011 May 24
40.Hung-Wen Lai, Su-Yu Chien, Shou-Jen Kuo, Ling-Ming Tseng, Chin-Wen Chi, Dar-Ren Chen* and Hui-Yi Lin.: The Potential Utility of Curcumin in the Treatment of HER-2-overexpressed Breast Cancer- An in vitro and in vivo Comparison Study with Herceptin, (Evid Based Complement Alternat Med. 2012;2012:486568. Epub 2011 Jun 6)
41.Yen PL, Chen DR, Yeh KT, Chu PY: Development of a stiffness measurement accessory for ultrasound in breast cancer diagnosis Med Eng Phys. 2011 May 27. [Epub ahead of print]
42.Dar-Ren Chen*, Hung-Wen Lai: Three-dimensional Breast Ultrasound for Malignt Detection ( invited review article, Expert Opinion on Medical Diagnostics)
43.Hung-Wen Lai, Shou-Jen Kuo, Sam Li-Sheng Chen, Chin-Wen Chi, Shou-Tung Chen, Tsai-Wang Chang, Dar-Ren Chen*: Prognostic significance of triple negative breast cancer at tumor size 1 cm and smaller (Eur J Surg Oncol. 2011 Jan;37(1):18-24. Epub 2010 Nov 19)
44.C. Lin, D. R. Chen* ,Chang KJ,Chang TW,Wang HC: The Pathologic Complete Response Rate and Toxicity Profile of Combination Docetaxel with Cisplatin plus Trastuzumab in T2 Breast Cancer Patients – A phase II study (In press, Cancer Chemotherapy and Pharmacology)
45.Nai-Wen Chang, Dar-Ren Chen, Fei-Na Chen, Chingju Lin, Chen-Teng Wu: HER2 codon 655 Val allele decreases plasma HDL-cholesterol levels in breast cancer patients with tamoxifen therapy J Investig Med. 2011 Dec;59(8):1252-7. doi: 10.231/JIM.0b013e3182354923.
46.Lin C, Chien SY, Kuo SJ, Chen LS, Chen ST, Lai HW, Chang TW, Chen DR*: A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan Jpn J Clin Oncol. 2012 Jan 27. [Epub ahead of print]
47.Yao-Lung K, Dar-Ren C, Tsai-Wang C: Clinicopathological features of triple-negative breast cancer in Taiwanese Women Int J Clin Oncol. 2011 Apr 1. [Epub ahead of print]
48.Chen DR, Chen ST, Wang TW, Tsai CH, Wei HH, Chen GJ, Yang TC, Lin C, Lin PH.: Characterization of estrogen quinone-derived protein adducts and their identification in human serum albumin derived from breast cancer patients and healthy controls. Toxicol Lett. 2011 Feb 24 [Epub ahead of print]
49.D.-R. Chen, I.-P. Lien, Y.-L. Huang: Ultrasonic vascularization evaluation in breast cancer with neoadjuvant chemotherapy Int J CARS (2011) 6 (Suppl 1):S305–S366
50.Wu HS, Lai HW, Kuo SJ, Lee YT, Chen DR, Chi CW, Huang MH.: Competitive Edge of Laparoscopic Appendectomy Versus Open Appendectomy: A Subgroup Comparison Analysis. J Laparoendosc Adv Surg Tech A. 2011 Feb 1. [Epub ahead of print
51.Chen DR, Chien SY, Kuo SJ, Teng YH, Tsai HT, Kuo JH, Chung JG: SLC34A2 as a novel marker for diagnosis and targeted therapy of breast cancer ( Anticancer Res. 2010 Oct;30(10):4135-40
52.Chen DR, Huang YL, Lin SH : Computer-aided Diagnosis with Textural Features for Breast Lesions in Sonograms (Comput Med Imaging Graph. 2010 Dec 3. [Epub ahead of print] )
53.Chang HC, Chen ST, Chien SY, Kuo SJ, Tsai HT, Chen DR*: Capsaicin may induce breast cancer cell death through apoptosis-inducing factor involving mitochondrial dysfunction Hum Exp Toxicol. 2011 Feb 7
54.Hsin-Shun Tseng, Szu-Erh Chan, Shou-Jen Kuo, Dar-Ren Chen*: Acupuncture-related rapid dermal spread of breast cancer: a rare case J Breast Cancer. 2011 Dec;14(4):340-4. Epub 2011 Dec 27)
55.Wu YC, Tang CS, Huang HY, Liu CH, Chen YL, Chen DR, Lin YW: Chemical production in electrocautery smoke by a novel predictive model Eur Surg Res. 2011;46(2):102-7. Epub 2011 Jan 11
56.Chu-Chung Chou, Jai-Sing Yang, Hsu-Feng Lu, Siu-Wan Ip, Chyi Lo Chih-Chung Wu, Jing-Pin Lin, Nou-Ying Tang, Jing-Gung Chung, Ming-Jen Chou, Ying-Hock Teng, and Dar-Ren Chen*: Quercetin-mediated Cell Cycle Arrest and Apoptosis Involving Activation of a Caspase Cascade through the Mitochondrial Pathway in Human Breast Cancer MCF-7 Cells Arch Pharm Res Vol 33, No 8, 1181-1191, 2010
57.Kuo SJ, Chen TH, Yen AM, Chen DR, Chen LS. Optimal two-stage breast cancer screening for countries with intermediate or low incidence of breast cancer. J Eval Clin Pract. 2010 Aug 24. [Epub ahead of print]
58.Lu YS, Chen DR, Tseng LM, Yeh DC, Chen ST, Hsieh CM, Wang HC, Yeh HT, Kuo SH, Huang CS: Phase II study of docetaxel, capecitabine, and cisplatin as neoadjuvant chemotherapy for locally advanced breast cancer. Cancer Chemother Pharmacol. 2010 Aug 11. [Epub ahead of print]
59.Kuo SJ, Chien SY, Lin C, Chan SE, Tsai HT, Chen DR*.: Significant elevations of CLDN16 and HAPLN3 gene expression in human breast cancer tissue Oncol Rep. 2010 Sep;24(3):759-66.
60.Che Lin, Su-Yu Chien, Dar-Ren Chen*: Nandrolone Abuse Aggravates Septic Shock (Kaohsiung J Med Sci. 2011 Jun;27(6):222-9. Epub 2011 Mar 31.
61.Yao-Li Chen, Hsin-Shun Tseng, Wu-Hsien Kuoe, Shun-Fa Yang, Dar-Ren Chen*, Hsiu-Ting Tsai* : Glutathione S-Transferase P1 (GSTP1) Gene Polymorphism Increases Age-Related Susceptibility of Hepatocellular Carcinoma ( BMC Genomics 2010, 11:46)
62.Yu-Chen Lee, Yao-Li Chen, Szu-Erh Chan, Hsin-Shun Tseng, Dar-Ren Chen*: Neuroendocrine Carcinoma of the Breast: Case Report and Literature Review ( Breast Care 2009;4:324-327)
63.Su-Yu Chien, Yao-Chung Wu, Jai-Sing Yang , Hsu-Feng Lu, Mei-Fen Tsou, W. G. Wood, Jing-Gung Chung, Dar-Ren Chen: Quercetin induced apoptosis acts through mitochondrial- and caspase-3- dependent pathways in human breast cancer MDA-MB-231 cells. Hum Exp Toxicol. 2009 Aug;28(8):493-503. Epub 2009 Sep 15
64.Po-Hsiung Lin, Dar-Ren Chen, Tzu-Wen Wang, Chia-Hua Lin, Ming-ChiehChuang, Po-Hsiung Lin: Investigation of the Cumulative Tissue Doses of Naphthoquinones in Human Serum Using Protein Adducts as Biomarker of Exposure Chem Biol Interact. 2009 Sep 14;181(1):107-14. Epub 2009 Jun 6.
65.Chia-Hua Lin, Ching-Lung Huang, Ming-Chieh Chuang, Ying-Jan Wang, Dar-Ren Chen, Shou-Tung Chen, and Po-Hsiung Lin: Protective Role of Estrogen Receptor-alpha on Lower Chlorinated PCB Congener-Induced DNA Damage and Repair in Human Tumoral Breast Cells (Toxicol Lett. 2009 Jul 10;188(1):11-9. Epub 2009 Feb 20)
66.Chen ST, Yi-Hsuan Hsiao, Yu-Len Huang, Wen-Miin Liang, Shou-Jen Kuo, Ming-Jen Chou, Dar-Ren Chen*: Comparative Analysis of Logistic Regression, Support Vector Machines and Artificial Neural Networks for 3D Power Doppler Imaging of Solid Breast Tumors. Korean J Radiol. 2009 Sep-Oct;10(5):464-71. Epub 2009 Aug 25.
67.Lin C, Chien SY, Chen LS, Kuo SJ, Chang TW, Chen DR*: Triple Negative Breast Carcinoma is a Prognostic Factor in Taiwanese Women. BMC Cancer. 2009 Jun 18;9(1):192. [Epub ahead of print]
68.Yu-Len Huang*, Chia-Chia Hsu, Yi-Hsuan Hsiao, Dar-Ren Chen*: Computer-aided Diagnosis for Breast Tumors by Using Vasculization of 3-D Power Doppler Ultrasound Ultrasound Med Biol. 2009 Oct;35(10):1607-14. Epub 2009 Aug 3.
69.Chang NW, Chen FN, Wu CT, Clin-Fen Lin, Chen DR*:Apolipoprotein E4 allele influences the response of plasma triglyceride levels to tamoxifen in breast cancer patients Clinica Chimica Acta 401 (2009) 144–147
70.Chu-Chung Chou, Yao-Chung Wu, Yu-Fen Wang, Ming-Chih Chou, Shou-Jen Kuo, Dar-Ren Chen*: Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through caspase-independent pathway (Oncol Rep. 2009 Mar;21(3):665-71)
71.Yi-Hsuan Hsiao, Yu-Len Huang, Wen-Miin Liang, Shou-Jen Kuo, Dar-Ren Chen*: Characterization of Benign and Malignant Solid Breast Masses: Harmonic versus Non-harmonic 3D Power Doppler Imaging (Ultrasound Med Biol. 2009 Mar;35(3):353-9. Epub 2008 Nov 28.)
72.Tseng HS, Chen YL, Chen ST, Wu YC, Kuo SJ, Chen LS, Wu HK, Chen DR*: The Management of Papillary Lesion of the Breast by Core-needle Biopsy. EJSO 35 (2009) 21-24
73.Yen PL, Chen DR, Yeh KT, Chu PY.: Lateral exploration strategy for differentiating the stiffness ratio of an inclusion in soft tissue. Med Eng Phys. 2008 Oct;30(8):1013-9. Epub 2008 May 20.
74.Chen D, Chu CY, Chen CY, Yang HC, Chiang YY, Lin TY, Chiang IP, Chuang DY, Yu CC, Chow KC: Expression of short form oncostatin M receptor as a decoy in lung adenocarcinomas (J Pathol. 2008 Jul;215(3):290-9)
75.Shou-Jen Kuo, Yu-Len Huang, Yi-Hsuan Hsiao, Dar-Ren Chen* : Vasculization of 3D Power Doppler Ultrasound Applied to Classify Benign and Malignant Breast Tumors by Using Neural Networks Ultrasound Obstet Gynecol. 2008 Jul;32(1):97-102
76.Yi-Hsuan Hsiao, Yu-Len Huang, Shou-Jen Kuo, Wen-Miin Liang,, Shou-Tong Chen, Dar-Ren Chen: Characterization of Benign and Malignant Solid Breast Masses in Harmonic 3D Power Doppler Imaging Eur J Radiol. 2009 Jul;71(1):89-95. Epub 2008 May 14.
77.Kuo SJ, Wang HC, Chow KC, Chiou SH, Chiang SF, Lin TY, Chiang IP, Chen DR*: Nuclear expression of rTSβ as a novel 5-fluorouracil resistance marker in patients with primary breast cancer Oncol Rep. 2008 Apr;19(4):881-8
78.Dar-Ren Chen, Yi-Hsuan Hsiao: Computer-Aided Diagnosis for Breast Ultrasound ( J Med Ultrasound 2008;16(1):46–56) Review Article
79.Huang SF, Chang RF, Moon WK, Lee YH, Chen DR, Suri JS.: Analysis of tumor vascularity using three-dimensional power Doppler ultrasound images. IEEE Trans Med Imaging. 2008 Mar;27(3):320-30
80.Yi-Hsuan Hsiao, Shou-Jen Kuo, Wen-Miin Liang, Yu-Len Huang, Dar-Ren Chen* : Intra-tumor Flow Index Can Predict the Malignant Potential of Breast Tumor: Dependent on Age and Volume (Ultrasound Med Biol. 2008 Jan;34(1):88-95)
81.Huang YL, Chen DR, Jiang YR, Kuo SJ, Wu HK, Moon WK.: Computer-aided Diagnosis with Morphological features for Breast Lesion on Sonograms Ultrasound Obstet Gynecol. 2008 Sep;32(4):565-72.
82.Yung-Hsien Liu, Mu-Tai Liu1, Dar-Ren Chen, Wen-Tao Huang, Ai-Yih Wang, Wen-Shan Liu, Tung-Hao Chang, Chu-Ping Pi, Chao-Yuan Huang: Occult Breast Cancer Presenting Aa Axillary Nodal Metastasis - A Case Report and Review of the Literature Therapeut Radiol Oncol 2007; 14(1): 57-62
83.Chang RF, Chang-Chien KC, Takada E, Suri JS, Moon WK, Wu JK, Cho N, Wang YF, Chen DR.: Breast Density Analysis in 3-D Whole Breast Ultrasound Images Conf Proc IEEE Eng Med Biol Soc. 2006;1(1):2795-2798.
84.Chang RF, Chang-Chien KC, Takada E, Suri JS, Moon WK, Wu JK, Cho N, Wang YF, Chen DR.: Three Comparative Approaches for Breast Density Estimation in Digital and Screen Film Mammograms Conf Proc IEEE Eng Med Biol Soc. 2006;1(1):4853-4856.
85.Hsien-Wen Kuo, Suze-Yuan Chou, Tsung-Wen Hu, Fang-Yang Wu, Da-Jen Chen: Urinary 8-hydroxy-2’ -deoxyguanosine _ (8-OHdG) and genetic polymorphisms in breast cancer Mutat Res. 2007 Jul 10;631(1):62-8.
86.Jeffery H.K. Wu, Ruey-Feng Chang, Ching-Lin Wang, Cheng-Shyong Chang, Shou-Jen Kuo, Shou-Tung Chen, Woo Kyung Moon, Ta-Hsun Kuo, Dar-Ren Chen*: Tamper Detection and Recovery for Medical Image Using Nearly Lossless Information Hiding Technique J Digit Imaging. 2008 Mar;21(1):59-76
87.Chang RF, Huang SF, Moon WK, Lee YH, Chen DR: Solid Breast Masses: Neural Network Analysis of Vascular Features at Three-dimensional Power Doppler US for Benign or Malignant Classification. Radiology. 2007 Apr;243(1):56-62. Epub 2007 Feb 20.
88.Chang RF, Huang SF, Wang LP, Chen D, Moon W.: Microcalcification detection in 3-d breast ultrasound Conf Proc IEEE Eng Med Biol Soc. 2005;6:6297-300
89.Y. L. Huang, D.R. Chen: Automatic contouring for breast tumors in 2-d sonography. Conf Proc IEEE Eng Med Biol Soc. 2005;3:3225-8.
90.Y. L. Huang, S.H. Lin, D.R. Chen:Computer-Aided Diagnosis Applied to 3-D US of Solid Breast Nodules by Using Principal Component Analysis and Image Retrieval. Conf Proc IEEE Eng Med Biol Soc. 2005;2:1802-5.
91.Y. L. Huang, K. L. Wang , D. R. Chen, "Diagnosis of Breast Tumors with Ultrasonic Texture Analysis Using Support Vector Machines", Neural Computing and Applications, vol. 15, no. 2, pp.164-169, Apr. 2006. (NSC 93-2213-E-029-014)
92.Huang YL, Jiang YR, Chen DR, Moon WK: Level Set Contouring for Breast Tumor in Sonography. J Digit Imaging. 2007 Jan 24; [Epub ahead of print]
93.Wu HD, Chou SY, Chen DR, Kuo HW: Differentiation of serum levels of trace elements in normal and malignant breast patients Biol Trace Elem Res. 2006 Oct;113(1):9-18
94.Chang RF, Huang SF, Moon WK, Lee YH, Chen DR: Computer algorithm for analysing breast tumor angiogenesis using 3-D power Doppler ultrasound Ultrasound Med Biol.2006 Oct;32(10):1499-508
95.Chen CJ, Chang RF, Moon WK, Chen DR*: 2-D ultrasound strain images for breast cancer diagnosis using nonrigid subregion registration. Ultrasound Med Biol. 2006 Jun;32(6):837-46.
96.Wu YC, Chen DR*, Kuo SJ Personal Experience of Ultrasound-guide 14 gauge Core Biopsy of Breast Tumor Eur J Surg Oncol. 2006 Jun 32(7); 715-718
97.Shou-Jen Kuo, Dar-Ren Chen*: Expression of glucose transporter-1 in Taiwanese patients with breast carcinoma – a preliminary report. Kaohsiung J Med Sci. 2006 Jul;22(7):339-45
98.Woo Kyung Moon, Ruey-Feng Chang, Chii-Jen Chen, Wei-Liang Chen, Dar-Ren Chen*:Solid breast masses: classification with computer-aided analysis of continuous US images obtained with probe compression Radiology. 2005 Aug;236(2):458-64
99.Shou-Jen Kuo , Kung-Tao Yang, Dar-Ren Chen*: Objective and Noninvasive Detection of Sub-clinical Lung Injury in Breast Cancer Patients after Radiotherapy Eur J Surg Oncol. 2005 Nov;31(9):954-7.
100. Hung YL, Kuo SJ, Chang CS, Lieu YK, Moon WK, Chen DR*: Image Retrieval with Principal Component for Breast Cancer Diagnosis on Various Ultrasound System Ultrasound Obstet Gynecol. vol. 26, no. 5, pp.558-566, October 2005
101. Chen DR*, Chang RF, Chen CJ, Ho MF, Kuo SJ, Chen ST, Hung SJ, Moon WK: Classification of breast ultrasound images using fractal feature. Clin Imaging. 2005 Jul-Aug;29(4):235-45
102. Chen WM, Chang RF, Kuo SJ, Chang CS, Moon WK, Chen ST, Chen DR*: 3-D ultrasound texture classification using run difference matrix Ultrasound Med Biol. 2005 Jun;31(6):763-70
103. Huang YL, Chen DR: Support vector machines in sonography Application to decision making in the diagnosis of breast cancer. Clin Imaging. 2005 May-Jun;29(3):179-84
104. Chang NW, Chen DR, Wu CT, Aouizerat BE, Chen FN, Hung SJ, Wang SH, Wei MF, Chang CS: Influences of apolipoprotein E polymorphism on the risk for breast cancer and Her2/neu status in Taiwan. Breast Cancer Res Treat. 2005 Apr;90(3):257-61
105. Ruey-Feng Chang, Wen-Jie Wu, Dar-Ren Chen*, Woo Kyung Moon: Mophology Based Automatic Ultrasound Segmentation and Diagnosis of Solid Breast Tumors. Breast Cancer Res Treat. 2005 Jan;89(2):179-85
106. Yu-Len Hung, Dar-Ren Chen: Watershed Segmentation for Breast Tumor in 2-D Sonography. Ultrasound in Medicine & Biology 2004 May; 30(5): 625-632
107. Dar-Ren Chen*, Ruey-Feng Chang, Chii-Jen Chen, Chih-Chia Chang, Long-Bin Jeng: Three-dimensional ultrasound in margin evaluation for breast tumor excision using Mammotome. Ultrasound in Medicine & Biology 2004 February 30(2): 169-179
108. Lee JH, Lu HF, Wang DY, Chen DR, Su CC, Chen YS, Yang JH, Chung JG. : Effects of tamoxifen on DNA adduct formation and arylamines N-acetyltransferase activity in human breast cancer cells. Res Commun Mol Pathol Pharmacol. 2004;115-116:217-33.
109. Huang SF, Chang RF, Chen DR, and Moon WK: Detection of Spiculation in Three- Dimensional Breast Ultrasound, IEEE Trans Med Imaging. 2004 Jan; 23(1): 111-21
110. Chang RF, Wu WJ, Moon WK, Chen WM, Lee W, Chen DR*: Segmentation of breast tumor in three-dimensional ultrasound images using three-dimensional discrete active contour model. Ultrasound Med Biol. 2003 Nov; 29(11):1571-81
111. Chen WM, Chang RF, Moon WK, Chen DR*: Segmentation of Breast Tumor in 3D Ultrasound Images Using 3D Discrete Active Contour Model. Ultrasound in Medicine & Biology 2003 July; 29(7): 1027-1035.
112. Chang RF, Wu WJ, Tseng CC, Chen DR, Moon WK: 3D Snake for US in Margin Evaluation for Malignant Breast Tumor Excision Using Mammotome. IEEE Trans Inf Technol Biomed. 2003 Sep;7(3):197-201
113. Chen WM, Chang RF, Moon WK, Chen DR*: Breast cancer diagnosis using three-dimensional ultrasound and pixel relation analysis. Ultrasound in Medicine & Biology 2003 July; 29(7): 1027-1035.
114. Chen DR*, Chang RF, Wu WJ, Moon WK, Wu WL: 3-D breast ultrasound segmentation using active contour model. Ultrasound in medicine & biology 2003 July; 29(7): 1017-1026.
115. Chang RF, Wu WJ, Chen DR*, Chen WM, Shu W, Lee JH, Jeng LB: 3-D US frame positioning using speckle decorrelation and image registration. Ultrasound in Medicine & Biology 2003 June; 29(6): 801-812.
116. Ruey-Feng Chang, Wen-Jie Wu, Woo Kyung Moon, Dar-Ren Chen*: Improvement in breast tumor discrimination by support vector machines and speckle-emphasis texture analysis. Ultrasound In Medicine & Biology 2003 May; 29(5): 679-686.
117. Dar-Ren Chen*, Ruey-Feng Chang, Wei-Ming Chen, Woo Kyung Moon: Computer Aided Diagnosis for Three-Dimensional Breast Ultrasound. Archives of Surgery 2003 March; 138(3): 296-302.
118. Ruey-Feng Chang, Wen-Jie Wu, Woo Kyung Moon Dar-Ren Chen*: Support Vector Machines for Diagnosis of Breast Tumor in Ultrasonic Images. Academic Radiology 2003 February; 10(2): 189-197.
119. Chen DR, Jeng LB, Kao A., Lin CC, Lee CC: Comparing Thallium-201 Spect Mammoscintigraphy and Ultrasonography to Detect Breast Cancer in Mammographical Dense Breasts. Neoplasma 2003; 50(3): 222-226.
120. Fang-Yang Wu, Yi-Ju Lee, Dar-Ren Chen, Hsien-Wen Kuo: Association of DNA-protein crosslinks and breast cancer. Mutation Research, 2002, 501: 69-78.
121. Hsein Wen Kuo, Sun Fan Chen, Wu Chin Ching, Dar-Ren Chen, Jau Hung Lee: Serum and Tissue Trace Element in Patient with breast Cancer in Taiwan. Biological Trace Element Research 2002 89(1): 1-11.
122. Wang HC, Chen DR, Kao CH, Lin CC, Lee CC: Detecting breast cancer in mammographically dense breasts: comparing technetium-99m tetrofosmin mammoscintigraphy and ultrasonography. Cancer Investigation 2002; 20(7-8): 932-8.
123. Chen DR, Jeng LB, Kao A, Lin CC, Lee CC: Usefulness of ammoscintigraphy with thallium-201 single photon emission computed tomography to differentiate palpable breast masses of young Taiwanese women when comparing with mammography. Neoplasma 2002; 49(5): 334-337.
124. Dar-Ren Chen*, Ruey-Feng Chang, Wen-Jia Kuo, Ming-Chun Chen, and Yu-Len Huang: Ultrasonic Medical Image Diagnosis of Breast Tumors Using Wavelet Transform and Neural Networks. Ultrasound in Medicine & Biology 2002 October; 28(10): 1301-1310.
125. Dar-Ren Chen*, Ruey-Feng Chang, Jau-Hong Lee: Three-Dimensional Breast Ultrasound Imaging in Patient with Nipple Discharge: A pictorial review of 27 cases. Journal of Medical Ultrasound, 2002; 10(2): 69-75.
126. Dar-Ren Chen*, Wen-Jia Kuo, Ruey-Feng Chang, Woo Kyung Moon , Cheng Chun Lee: Computer-aided Diagnostic Sonomammography with Bootstrap Technique for Small Training Sets. Ultrasound in Medicine & Biology 2002; 7: 897-902.
127. Wen-Jia Kuo, Ruey-Feng Chang, Cheng Chun Lee, Woo Kyung Moon, Dar-Ren Chen* : Retrieval Technique for the Diagnosis of Solid Breast Tumor on Sonogram. Ultrasound in Medicine & Bology 2002; 7: 903-909.
128. Kim-Choy Ng, Chee-Keong Tan, Shih-Wei Lai, Dar-Ren Chen, Wei-Kung Chen: Mucocele of the Appendix with Hematuria. The Yale journal of biology and medicine 2001; 74: 9-12
129. Wen-Jia Kuo, Ruey-Feng Chang, Dar-Ren Chen*, Woo Kyung Moon: Computer-aided Diagnosis of Breast Tumors with Different Ultrasound Systems. Academic Radiology 2002; 9:793-799.
130. Dar-Ren Chen*, Ruey-Feng Chang, Tz-Yi Lin, Mei-DueYang: Papillary Disease of Breast: High Resolution US and 3D Imaging Appearances. Journal of Medical Ultrasound, 2001; 9(3): 147-149.
131. Wen-Jia Kuo, Ruey-Feng Chang, Dar-Ren Chen*, Cheng Chun Lee: Data Mining with Decision Trees for Diagnosis of Breast Tumor in Medical Ultrasonic Images. Breast Cancer Research and Treatment, 2001; 66:51-57.
132. Shian-Min Liu and Dar-Ren Chen: Signet-ring Cell Carcinoma of the Breast. Pathology International 2000; 500: 67-70.
133. Dar-Ren Chen*, Ruey-Feng Chang, Yu-Len Huang, Yi-Hong Chou, Chui-Mei Tiu, Po-Pang Tsai: Texture Analysis of Breast Tumors on Sonograms. Seminars in Ultrasound, CT and MR 2000; 4(21): 308-316.
134. Ruey-Feng Chang, Wen-Jia Kuo, Dar-Ren Chen*, Yu-Len Huang, Jau-Hong Lee, Yi-Hong Chou: Computer-Aided Diagnosis for Surgical Office-Based Breast Ultrasound. Archives of Surgery 2000; 135: 696-699.
135. Dar-Ren Chen*, Ruey-Feng Chang, Yu-Len Huang: Breast Cancer Diagnosis Using Self-Organizing Map for Sonography. Ultrasound in Medicine & Biology 2000; 3: 405-411.
136. Yung-Fanng Chen, Hsein-Jar Chiang, Jan-Horng Lee, Dar-Ren Chen, Chung-Yi Lin, Yuan-Horng Tzeng, Ruey-Fen Chen: Percutaneous Transhepatic Removal of Bile Duct Stones Chin J Radiol 2000; 25:1-5
137. Dar-Ren Chen*, Ruey-Feng Chang, Yu-Len Huang: Computer-aided Diagnosis applied to US of Solid Breast Nodules by Using Neural Networks. Radiology 1999; 213: 407-412.
138. Dar-Ren Chen*, Kuo-Juei Lin., Wen-Miin Liang, Hsien-Wen Kuo, Rey-Feng Chang: Computerized Quantitative Assessment of Sonomammographic Homogeneity between Fibroadenoma and Carcinoma of Breast. Journal of Medical Ultrasound 1999; 7:157-162
139. Dar-Ren Chen*, Ruey-Feng Chang, Hsien-Wen Kuo, Kuo-Juei Lin, Jau- Hong Lee: Computerized Quantitative Assessment of Echogenicity of Breast Fibroadenoma. Journal of Medical Ultrasound 1999; 7: 11-17).
140. Kim-Choy Ng, Jau-Hong Lee, Dar-Ren Chen, Ke-Chang Huang: A Rare Cause of Obstructive Jaundice-Biliary Tuberculosis Associated with Intrahepatic Stone. Medical Journal of China Medical College and Hospital 1997; 2:192-197
141. Jau-Hong Lee, Dar-Ren Chen, Shin-Cheng Pang, Yih-Syhong Lai: Mucinous Biliary Cysadenoma with mesenchymal stroma; Expression of CA 19-9 and CEA in the serum and cystic fluid. Journal of Gastroenterology. 1996; 31:732 |
國內首創推廣整型式乳癌切除手術 乳癌超音波診斷暨微創手術 乳癌相關之化療、標靶治療及賀爾蒙治療
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| 蘇進成 主治醫師
最高學歷: 中國醫藥大學 醫學博士(2003/09~2006/06)
醫師證照: 台灣外科醫學會 外科專科醫師 台灣消化外科醫學會 消化外科專科醫師 台灣乳房醫學會 乳房外科專科醫師 台灣臨床腫瘤醫學會 臨床腫瘤專科醫師 中華民國醫用超音波學會 超音波專科醫師 世界中醫藥學會第一屆腫瘤專業委員會理事 美國癌症研究協會 (American Association for Cancer Research) 會員 美國臨床腫瘤醫學會 (American Society of Clinical Oncology) 會員
經歷: 中國醫藥大學附設醫院 一般外科主治醫師 (1998/07~2005/12) 花蓮慈濟醫學中心 一般外科主任 (2007 /07 ~2008/11) 花蓮慈濟醫學中心 乳房中心主任 ( 2008/ 12~2010/ 06) 慈濟大學醫學系 專任助理教授 彰化基督教醫院 體系乳房中心 協同主任 (2011 / 01 ~2015/06) 鹿港基督教醫院 乳房中心主任 (2011 / 01 ~2015/06) 明道大學 兼任副教授
現任: 彰化基督教醫院 外科部 部協同主任 (2011 / 01 ~迄今) 彰化基督教醫院 中西醫結合腫瘤研究中心 主任 (2012 / 01 ~迄今) 彰化基督教醫院 全方位乳房腫瘤中心 主治醫師 (2011/01迄今 中國醫藥大學 兼任助理教授
最近五年 國際期刊發表 1. Chuang WL ,*Su CC , Lin PY , Lin CC , Chen YL. Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways. Mol Med Rep. 2015 Aug;12(2):1677-84. doi: 10.3892/mmr.2015.3573. Epub 2015 Mar 31. (SCI)
2. *Su CC, Chen CJ , Kuo SJ , Chen DR . Myoid hamartoma of the breast with focal chondromyoxid Metaplasia and pseudoangiomatous stromal hyperplasia: A case report. Oncol Lett. 2015 Apr; 9(4):1787-1789. Epub 2015 Jan 23. (SCI)
3. *Su CC. Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC 3 pancreatic carcinoma cells. Mol Med Rep. 2015 Apr; 11(4):3160-6. doi: 10.3892/mmr.2014.3090. Epub 2014 Dec 15. (SCI)
4. *Su CC. Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression. Anticancer Res. 2014 Dec; 34(12):7097-110. (SCI)
5. *Su CC. Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing Bip, TCTP, Mcl-1 and Bcl-xL and increasing Bax and CHOP protein expression. International Journal of Molecular Medicine. 2014 Sep 29. Doi:10.3892/ijmm.2014.1949. Epub 2014 Sep 29. (SCI)
6. Lai HW, Tseng LM, Chang TW, Kuo YL, Hsieh CM, Chen ST, Kuo SJ, * Su CC, Chen DR. The prognostic significance of metaplastic carcinoma of the breast (MCB)--a case controlled comparison study with infiltrating ductal carcinoma. Breast. 2013 Oct; 22(5):968-73. doi: 10.1016/j.breast.2013.05.010. Epub 2013 Jun 17.
7. Chien SY, Kuo SJ, Chen DR, *Su CC. Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl 1 and TCTP and increases that of TNF-α and Bax in BxPC 3 pancreatic carcinoma cells. International Journal of Molecular Medicine. 2013 Jul;32(1):85-92. doi: 10.3892/ijmm.2013.1369. Epub 2013 May 8. (SCI)
8. Chen YL, Yan MY, Chien SY, Kuo SJ, Chen DR, Cheng CY, *Su CC. Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro. Mol Med Rep. 2013 May;7(5): 1487-93. doi: 10.3892/mmr.2013.1381. Epub 2013 Mar 20. (SCI)
9. Huang CY, Chiu TL, Kuo SJ, Chien SY, Chen DR, *Su CC. Tanshinone IIA inhibits the growth of pancreatic cancer BxPC 3 cells by decreasing protein expression of TCTP, MCL 1 and Bcl xL. Mol Med Rep. 2013 Mar;7(3):1045-9. doi: 10.3892/mmr.2013.1290. Epub 2013 Jan 25. (SCI)
10. Chiu TL, Wang MJ, *Su CC. The treatment of glioblastoma multiforme through activation of microglia and TRAIL induced by rAAV2-mediated IL-12 in a syngeneic rat model. J Biomed Sci. 2012 Apr 22;19:45. doi: 10.1186/1423-0127-19-45. (SCI)
11. *Su CC. Tanshinone IIA potentiates the efficacy of 5-FU in Colo205 colon cancer cells in vivo through downregulation of P-gp and LC3-II. Exp Ther Med. 2012 Mar;3(3):555-559. Epub 2011 Dec 28.
12. Yan MY, Chien SY, Kuo SJ, Chen DR, *Su CC. Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression. International Journal of Molecular Medicine. 2012 May;29(5):855-63. doi: 10.3892/ijmm.2012.908. Epub 2012 Feb 7. (SCI)
13.*Su CC, Chien SY, Kuo SJ, Chen YL, Cheng CY, Chen DR. Tanshinone IIA inhibits human breast cancer MDA-MB-231 cells by decreasing LC3-II, Erb-B2 and NF-κBp65. Mol Med Rep. 2012 Apr;5(4):1019-22. doi: 10.3892/mmr.2012.756. Epub 2012 Jan 13. (SCI)
14. Chien SY, Kuo SJ, Chen YL, Chen DR, Cheng CY, *Su CC. Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo. Mol Med Rep. 2012 Jan;5(1):282-6. doi: 10.3892/mmr.2011.631. Epub 2011 Oct 14. (SCI)
15. Chan SE, Lai HW, *Su CC, Kuo SJ, Chien SY, Lin HY, Chen DR. Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study. Evid Based Complement Alternat Med. 2011;2011:841564. doi: 10.1155/2011/841564. Epub 2011 May 24.
16. Cheng CY, *Su CC. Tanshinone IIA may inhibit the growth of small cell lung cancer H146 cells by up-regulating the Bax/Bcl-2 ratio and decreasing mitochondrial membrane potential. Mol Med Rep. 2010 Jul-Aug;3(4):645-50. doi: 10.3892/mmr_00000310. (SCI)
17. Cheng CY, Lin YH, *Su CC. Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model. Mol Med Rep. 2010 Mar-Apr;3(2):227-31. doi: 10.3892/mmr_00000244. (SCI)
18. Cheng CY, Lin YH, *Su CC. Curcumin inhibits the proliferation of human hepatocellular carcinoma J5 cells by inducing endoplasmic reticulum stress and mitochondrial dysfunction. International Journal of Molecular Medicine. 2010 Nov;26(5):673-8. (SCI)
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乳房超音波檢查 乳房良性腫瘤 整形式切除手術 乳房腫瘤 超音波導引 切片及微創手術 乳房攝影細針定位後 鈣化切片手術 乳癌整形式腫瘤切除手術及乳癌化療 中西醫結合癌症治療研究
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| 胡華? 主治醫師
經歷: 馬偕紀念醫院放射科住院醫師 美國南加州大學受訓 教育部部定講師 中華民國放射診斷科專科醫師 彰化基督教醫院影像醫學部主治醫師 彰化基督教醫院影像醫學部協同主任 |
乳房攝影檢查 頭頸部之電腦斷層檢查 頭頸部之磁振掃描檢查 一般及特殊放射線檢查.判讀 全身血管攝影檢查 侵入性.治療性放射線治療
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| 王全正 主治醫師
經歷: 臺大醫院 血液科 總醫師 臺大醫院 腫瘤醫學部 總醫師 國家衛生研究院 癌症研究組 主治醫師 臺大醫院 腫瘤醫學部 兼任主治醫師 中山醫學大學附設醫院 腫瘤內科 主治醫師
現任: 彰化基督教醫院 血液腫瘤科主治醫師 |
固態腫瘤之診斷與治療 (如:鼻咽癌、頭頸部癌、胃癌、大腸直腸癌、乳癌、…等)
血液疾病之診斷與治療 (如:貧血、淋巴瘤、多發性骨髓瘤、白血病、血小板低下等)
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| 曾信順 主治醫師
經歷: 台中榮民總醫院實習醫師 彰化基督教醫院外科部住院醫師 彰化基督教醫院外科部總醫師 彰化基督教醫院一般外科臨床研究醫師 彰化基督教醫院研究部研究醫師 彰化基督教醫院研究部癌症醫學研究室成員 彰化基督教醫院研究部生物統計研究室共同主持人 彰化基督教醫院外科病房主任 彰化基督教醫院人體器官保存庫負責人 彰化基督教醫院組織檢體庫負責人 國立台灣大學流行病學研究所博士生
現任: 彰化基督教醫院全方位乳房醫學中心專科醫師 彰化基督教醫院一般外科主治醫師 中華民國癌症醫學會會員 台灣外科專科醫學會會員 台灣外科專科醫師 中華民國消化系外科醫學會會員 中華民國消化系外科專科醫師 台灣內試鏡外科醫學會會員 台灣內試鏡外科專科醫師 中華民國乳房醫學會會員 中華民國乳房醫學專科醫師 台灣血管外科學會會員 台灣血管外科專科醫師 |
乳房疾病預防篩檢 乳癌診斷治療 乳房超音波檢查及導引切片手術 乳癌預防諮詢 乳房外科手術 週邊血管外科 腫瘤外科 消化系外科 甲狀腺癌 內分泌外科 腸胃道手術 腹腔鏡手術 人工血管手術 腹股溝疝氣及各類腹腔疝氣手術 各類皮下腫塊之診斷與治療 |
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| 賴鴻文 主治醫師
學歷: 國立成功大學醫學士 1995/09 至 2001/06 國立陽明大學 藥理學研究所 博士2007/09 至 2011/06
經歷: 彰化基督教醫院 癌症篩檢整合中心 主任 2009/08 至 2010/06 彰化秀傳、彰濱秀傳一般外科主治醫師2007/07 至 2009/08 台北榮民總醫院一般外科主治醫師 2007/06 至 2007/07
現職: 彰化基督教醫院 一般外科 主治醫師2009/08迄今 彰化基督教醫院 乳癌預防及篩檢整合中心 主任2010/07迄今 彰化基督教醫院 乳腺醫師養成訓練中心 副主任2010/07迄今 國立陽明大學 醫學院 外科講師 2008/03迄今
國外進修: 日本東京女子醫科大學附設醫院 消化系中心進修2008/11 日本東京龜田醫院(Kameda Medical Center)進修內視鏡乳房手術2010/05 義大利米蘭歐洲癌症中心(European Institute Oncology)進修腫瘤整形式乳癌手術(Oncoplastic Breast Surgery)及乳房重建整形訓練 2010/10至 2011/4
醫師證照: 台灣外科醫學會專科醫師 台灣消化外科醫學會專科醫師 台灣乳房醫學會專科醫師 台灣創傷外科醫學會專科醫師 台灣內視鏡外科醫學會專科醫師 衛生署定肝臟及腎臟移植合格醫師 台灣內分泌外科醫學會專科醫師 台灣醫用超音波醫學會 外科超音波專業醫師 乳房及腹部超音波高級班訓練證照 |
乳房疾病之診斷與治療 乳癌手術治療及術後化療 乳房超音波及超音波下引導切片 細針定位切片 乳房腫瘤整形式手術(Oncoplastic surgery)及乳房重建 乳頭及乳暈重建 肝臟及腎臟移植 肝膽胰及各種胃腸道外科疾病 腹腔鏡手術 創傷處理 手術治療甲狀腺疾病診斷治療及開刀 疝氣之診斷與處理 肛門疾病痔瘡?管之診斷與治療 大腸直腸腫瘤手術 |
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| 林(吉吉) 主治醫師
經歷: 臺大醫院外科總醫師及外科臨床研究員 長榮大學醫學研究所碩士班 美國腸道及靜脈營養學會會員 美國外科醫學會認證外傷急救資格 中華民國外科專科醫師 中華民國消化外科專科醫師 中華民國內視鏡外科專科醫師
現任: 一般外科主治醫師 彰化醫學 醫學雜誌編輯 |
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| 廖淑芬 主治醫師
學歷: 國立陽明醫學院醫學系畢業(1986-1993)
經歷 台北榮民總醫院復健科住院醫師(1993-1997) 台北榮民總醫院復健科總醫師 灣橋榮民醫院復健科主治醫師 元吉醫院復健科主任 澳洲Cathley-Smith lymphedema 治療進修 中台醫護技術學院放射科病理學兼任講師(2002-2004
現職: 彰化基督教醫院復健科資深主治醫師(2001迄今) 彰化基督教醫院兒童發展聯合評估中心遲緩鑑定醫師 台灣兒童暨家扶基金會附設彰化宜智學園醫療顧問 教育部部定助理教授(助理字第017088號) |
淋巴水腫復健 兒童復健及早期療育 神經復健 運動醫學 神經肌電圖檢查 |
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| 林敬翰 主治醫師
學歷 東海大學畜產與生物科技學系博士班 經歷 台灣乳房腫瘤手術暨重建醫學會副祕書長 彰化基督教醫院乳房外科臨床研究醫師 彰化基督教醫院一般外科總醫師 現任 彰化基督教醫院一般外科主治醫師 彰化基督教醫院乳房腫瘤中心主治醫師 彰化基督教醫院癌症醫學研究中心副主任 員林基督教醫院乳房外科主治醫師 專科 台灣外科醫學會專科醫師 台灣乳房醫學會專科醫師 台灣乳房醫學會乳房外科專科醫師 中華民國醫用超音波學會會員 進修 美國紐約大都會醫院中心(Metropolitan Hospital Center)住院醫師 日本東京龜田醫院(Kameda Medical Center)內視鏡乳房手術進修 韓國首爾大林聖母醫院(Daerim St. Mary’s Hospital)乳房腫瘤微創手術進修 |
乳房疾病預防篩檢 乳癌診斷治療 乳房超音波檢查 乳房腫瘤微創與內視鏡手術 乳癌整形式腫瘤切除手 |
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